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KMID : 0383820150780030232
Tuberculosis and Respiratory Diseases
2015 Volume.78 No. 3 p.232 ~ p.238
Vitamin D Status in South Korean Military Personnel with Acute Eosinophilic Pneumonia: A Pilot Study
Jhun Byung-Woo

Kim Se-Jin
Kim Kang
Lee Ji-Eun
Hong Duck-Jin
Abstract
Background : A relationship between low vitamin D levels and the development or outcomes of respiratory diseases has been identified. However, there is no data on the vitamin D status in patients with acute eosinophilic pneumonia (AEP). We evaluated the vitamin D status in patients with AEP among South Korean military personnel.

Materials and Methods : We prospectively compared the serum levels of total 25-hydroxyvitamin D [25(OH)D], 25(OH)D3, and 25(OH)D2 among patients with AEP, pulmonary tuberculosis (PTB), and community-acquired pneumonia (CAP).

Results : In total, 65 patients with respiratory diseases, including AEP (n=24), PTB (n=19), and CAP (n=22), were identified. Of the 24 patients with AEP, 2 (8%) had deficient total 25(OH)D levels (<10 ng/mL), 17 (71%) had insufficient total 25(OH)D levels (¡Ã10 to <30 ng/mL), and only 5 (21%) had sufficient total 25(OH)D levels (¡Ã30 to <100 ng/mL). The difference in the total 25(OH)D levels among patients with AEP, PTB, and CAP was not statistically significant (p=0.230). The median levels of total 25(OH)D, 25(OH)D3, and 25(OH)D2 were 22.84, 22.84, and 0.00 ng/mL, respectively, and no differences in the 25(OH)D level were present among patients with AEP, PTB, and CAP with the exception of the total 25(OH)D level between patients with AEP and PTB (p=0.042).

Conclusion : We have shown that low vitamin D levels are frequently found in patients with AEP and are comparable with those in patients with PTB and CAP.
KEYWORD
Deficiency, Pulmonary Eosinophilia, Pneumonia, Vitamin D
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